Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice

Human sarcomas arise suddenly, thus preempting the study of preneoplastic and early neoplastic lesions. To explore the natural history of these tumors we studied male mice carrying a heterozygous deletion of p53 and an activated HER-2/neu transgene (BALB-p53Neu mice), that develop urethral rhabdomyo...

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Detalles Bibliográficos
Autores principales: Ianzano, Marianna L., Croci, Stefania, Nicoletti, Giordano, Palladini, Arianna, Landuzzi, Lorena, Grosso, Valentina, Ranieri, Dario, Dall'Ora, Massimiliano, Santeramo, Ilaria, Urbini, Milena, Giovanni, Carla De, Lollini, Pier-Luigi, Nanni, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960193/
https://www.ncbi.nlm.nih.gov/pubmed/24334679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960193/
https://www.ncbi.nlm.nih.gov/pubmed/24334679

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