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Peptide-Pulsed Dendritic Cells Have Superior Ability to Induce Immune-Mediated Tissue Destruction Compared to Peptide with Adjuvant

Vaccines for cancer immunotherapy are of interest but in general have not yet achieved the desired therapeutic efficacy in clinical trials. We present here a novel model to evaluate vaccine strategies by following tissue destruction in a transgenic model, where a defined antigen is expressed on panc...

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Detalles Bibliográficos
Autores principales:	Dissanayake, Dilan, Murakami, Kiichi, Tran, Michael D., Elford, Alisha R., Millar, Douglas G., Ohashi, Pamela S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960236/ https://www.ncbi.nlm.nih.gov/pubmed/24647761 http://dx.doi.org/10.1371/journal.pone.0092380

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