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Non-Enzymatic DNA Cleavage Reaction Induced by 5-Ethynyluracil in Methylamine Aqueous Solution and Application to DNA Concatenation

DNA can be concatenated by hybridization of DNA fragments with protruding single-stranded termini. DNA cleavage occurring at a nucleotide containing a DNA base analogue is a useful method to obtain DNA with designed protruding termini. Here, we report a novel non-enzymatic DNA cleavage reaction for...

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Detalles Bibliográficos
Autores principales: Ikeda, Shuji, Tainaka, Kazuki, Matsumoto, Katsuhiko, Shinohara, Yuta, Ode, Koji L., Susaki, Etsuo A., Ueda, Hiroki R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960239/
https://www.ncbi.nlm.nih.gov/pubmed/24647759
http://dx.doi.org/10.1371/journal.pone.0092369

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