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Rapid Strategy for Screening by Pyrosequencing of Influenza Virus Reassortants - Candidates for Live Attenuated Vaccines

BACKGROUND: Live attenuated influenza vaccine viruses (LAIVs) can be generated by classical reassortment of gene segments between a cold adapted, temperature sensitive and attenuated Master Donor Virus (MDV) and a seasonal wild-type (wt) virus. The vaccine candidates contain hemagglutinin (HA) and n...

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Detalles Bibliográficos
Autores principales:	Shcherbik, Svetlana V., Pearce, Nicholas C., Levine, Marnie L., Klimov, Alexander I., Villanueva, Julie M., Bousse, Tatiana L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960276/ https://www.ncbi.nlm.nih.gov/pubmed/24647786 http://dx.doi.org/10.1371/journal.pone.0092580

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