Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy

Bioassays that predict clinical outcome are essential to optimize cellular anticancer immunotherapy. We have recently developed a robust and simple skin test to evaluate the capacity of tumor-specific T cells to migrate, recognize their targets and exert effector functions. This bioassay detects T c...

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Autores principales: Wimmers, Florian, Aarntzen, Erik HJG, Schreibelt, Gerty, Jacobs, Joannes FM, JA Punt, Cornelis, Figdor, Carl G, de Vries, I Jolanda M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960298/
https://www.ncbi.nlm.nih.gov/pubmed/24653961
http://dx.doi.org/10.4161/onci.27219
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author Wimmers, Florian
Aarntzen, Erik HJG
Schreibelt, Gerty
Jacobs, Joannes FM
JA Punt, Cornelis
Figdor, Carl G
de Vries, I Jolanda M
author_facet Wimmers, Florian
Aarntzen, Erik HJG
Schreibelt, Gerty
Jacobs, Joannes FM
JA Punt, Cornelis
Figdor, Carl G
de Vries, I Jolanda M
author_sort Wimmers, Florian
collection PubMed
description Bioassays that predict clinical outcome are essential to optimize cellular anticancer immunotherapy. We have recently developed a robust and simple skin test to evaluate the capacity of tumor-specific T cells to migrate, recognize their targets and exert effector functions. This bioassay detects T cells with an elevated antineoplastic potential and hence rapidly identifies patients responding to immunotherapy.
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spelling pubmed-39602982014-03-20 Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy Wimmers, Florian Aarntzen, Erik HJG Schreibelt, Gerty Jacobs, Joannes FM JA Punt, Cornelis Figdor, Carl G de Vries, I Jolanda M Oncoimmunology Author's View Bioassays that predict clinical outcome are essential to optimize cellular anticancer immunotherapy. We have recently developed a robust and simple skin test to evaluate the capacity of tumor-specific T cells to migrate, recognize their targets and exert effector functions. This bioassay detects T cells with an elevated antineoplastic potential and hence rapidly identifies patients responding to immunotherapy. Landes Bioscience 2014-01-01 /pmc/articles/PMC3960298/ /pubmed/24653961 http://dx.doi.org/10.4161/onci.27219 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Wimmers, Florian
Aarntzen, Erik HJG
Schreibelt, Gerty
Jacobs, Joannes FM
JA Punt, Cornelis
Figdor, Carl G
de Vries, I Jolanda M
Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
title Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
title_full Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
title_fullStr Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
title_full_unstemmed Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
title_short Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
title_sort early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960298/
https://www.ncbi.nlm.nih.gov/pubmed/24653961
http://dx.doi.org/10.4161/onci.27219
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