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Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer

BACKGROUND: Androgen receptor (AR)-gene amplification, found in 20–30% of castration-resistant prostate cancer (CRPCa) is proposed to develop as a consequence of hormone-deprivation therapy and be a prime cause of treatment failure. Here we investigate AR-gene amplification in cancers before hormone...

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Detalles Bibliográficos
Autores principales:	Merson, S, Yang, Z H, Brewer, D, Olmos, D, Eichholz, A, McCarthy, F, Fisher, G, Kovacs, G, Berney, D M, Foster, C S, Møller, H, Scardino, P, Cuzick, J, Cooper, C S, Clark, J P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960602/ https://www.ncbi.nlm.nih.gov/pubmed/24481405 http://dx.doi.org/10.1038/bjc.2014.13

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