Cargando…

MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients

BACKGROUND: MicroRNAs (miRNAs) regulate the biological properties of colorectal cancer (CRC) cells and might serve as potential prognostic factors and therapeutic targets. In this study, we therefore globally profiled miRNAs associated with E-cadherin expression in CRC cells in an attempt to identif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pichler, M, Ress, A L, Winter, E, Stiegelbauer, V, Karbiener, M, Schwarzenbacher, D, Scheideler, M, Ivan, C, Jahn, S W, Kiesslich, T, Gerger, A, Bauernhofer, T, Calin, G A, Hoefler, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960623/ https://www.ncbi.nlm.nih.gov/pubmed/24504363 http://dx.doi.org/10.1038/bjc.2014.51

Ejemplares similares

Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer
por: Stotz, M, et al.
Publicado: (2013)

Validation of C-reactive protein levels as a prognostic indicator for survival in a large cohort of pancreatic cancer patients
por: Szkandera, J, et al.
Publicado: (2014)

Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells
por: Pehserl, Anna-Maria, et al.
Publicado: (2016)

Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma
por: Aigelsreiter, A, et al.
Publicado: (2013)

Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer
por: Pichler, M, et al.
Publicado: (2012)

The elevated preoperative platelet-to-lymphocyte ratio predicts poor prognosis in breast cancer patients
por: Krenn-Pilko, S, et al.
Publicado: (2014)

Elevated preoperative neutrophil/lymphocyte ratio is associated with poor prognosis in soft-tissue sarcoma patients
por: Szkandera, J, et al.
Publicado: (2013)

The preoperative lymphocyte to monocyte ratio predicts clinical outcome in patients with stage III colon cancer
por: Stotz, M, et al.
Publicado: (2014)

A derived neutrophil to lymphocyte ratio predicts clinical outcome in stage II and III colon cancer patients
por: Absenger, G, et al.
Publicado: (2013)

The derived neutrophil to lymphocyte ratio is an independent prognostic factor in patients with diffuse large B-cell lymphoma
por: Troppan, K, et al.
Publicado: (2014)

Validation of the pre-treatment neutrophil–lymphocyte ratio as a prognostic factor in a large European cohort of renal cell carcinoma patients
por: Pichler, M, et al.
Publicado: (2013)

Epithelial-mesenchymal transition-like events in vulvar cancer and its relation with HPV
por: Rodrigues, I S, et al.
Publicado: (2013)

Prolactin receptor is a negative prognostic factor in patients with squamous cell carcinoma of the head and neck
por: Bauernhofer, T, et al.
Publicado: (2011)

SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types
por: Richtig, Georg, et al.
Publicado: (2017)

Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer
por: Ress, Anna Lena, et al.
Publicado: (2014)

Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition
por: Krubasik, D, et al.
Publicado: (2006)

Epithelial-to-mesenchymal transition (EMT) induced by inflammatory priming elicits mesenchymal stromal cell-like immune-modulatory properties in cancer cells
por: Ricciardi, M, et al.
Publicado: (2015)

Disabled-2 downregulation promotes epithelial-to-mesenchymal transition
por: Martin, J C, et al.
Publicado: (2010)

Hypoxia, Snail and incomplete epithelial–mesenchymal transition in breast cancer
por: Lundgren, K, et al.
Publicado: (2009)

Low spinophilin expression enhances aggressive biological behavior of breast cancer
por: Schwarzenbacher, Daniela, et al.
Publicado: (2015)

New cellular tools reveal complex epithelial–mesenchymal interactions in hepatocarcinogenesis
por: Sagmeister, S, et al.
Publicado: (2008)

Tumour-initiating capacity is independent of epithelial–mesenchymal transition status in breast cancer cell lines
por: Xie, G, et al.
Publicado: (2014)

TBLR1 is a novel prognostic marker and promotes epithelial–mesenchymal transition in cervical cancer
por: Wang, J, et al.
Publicado: (2014)

Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis
por: de Graeff, P, et al.
Publicado: (2009)

Fucosylated TGF-β receptors transduces a signal for epithelial–mesenchymal transition in colorectal cancer cells
por: Hirakawa, M, et al.
Publicado: (2014)

EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205
por: Massoner, P, et al.
Publicado: (2014)

Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells
por: Comamala, M, et al.
Publicado: (2011)

The FGFR1 inhibitor PD173074 induces mesenchymal–epithelial transition through the transcription factor AP-1
por: Nguyen, P T, et al.
Publicado: (2013)

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas
por: Colomiere, M, et al.
Publicado: (2009)

High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability
por: Michel, S, et al.
Publicado: (2008)

Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial–mesenchymal transition in metastatic nasopharyngeal carcinoma
por: Horikawa, T, et al.
Publicado: (2011)

Epithelial to mesenchymal transition and HPV infection in squamous cell oropharyngeal carcinomas: the papillophar study
por: Lefevre, Marine, et al.
Publicado: (2017)

Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
por: Yu, Y, et al.
Publicado: (2014)

MDM2 promotes epithelial–mesenchymal transition and metastasis of ovarian cancer SKOV3 cells
por: Chen, Ying, et al.
Publicado: (2017)

Enhanced expression of peroxisome proliferator-activated receptor gamma in epithelial ovarian carcinoma
por: Zhang, G Y, et al.
Publicado: (2005)

Prognostic significance of epithelial–mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray
por: Nitta, T, et al.
Publicado: (2014)

Detection of circulating epithelial cells in the blood of patients with breast cancer: comparison of three techniques
por: Ring, A E, et al.
Publicado: (2005)

The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer
por: de Graeff, P, et al.
Publicado: (2008)

Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis
por: Peng, F, et al.
Publicado: (2013)

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer
por: Wigfield, S M, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_0r325plt0snmj2ghi19amkrpfd