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Host genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia

BACKGROUND: Host germline variations and their potential prognostic importance is an emerging area of interest in paediatric ALL. METHODS: We investigated the associations between 20 germline variations and various clinical end points in 463 children with ALL. RESULTS: After adjusting for known prog...

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Detalles Bibliográficos
Autores principales:	Lu, Y, Kham, S K Y, Ariffin, H, Oei, A M I, Lin, H P, Tan, A M, Quah, T C, Yeoh, A E J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960629/ https://www.ncbi.nlm.nih.gov/pubmed/24434428 http://dx.doi.org/10.1038/bjc.2014.7

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