Cargando…

Increased Expression of Chitinase 3-Like 1 in Aorta of Patients with Atherosclerosis and Suppression of Atherosclerosis in Apolipoprotein E-Knockout Mice by Chitinase 3-Like 1 Gene Silencing

Introduction. The purpose of this study was to investigate the changes of chitinase 3-like 1 (CHI3L1) in the aorta of patients with coronary atherosclerosis and to determine whether inhibition of CHI3L1 by lentivirus-mediated RNA interference could stabilize atherosclerotic plaques in apolipoprotein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Zushun, Xing, Shanshan, Zheng, Fei, Xing, Qichong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960764/ https://www.ncbi.nlm.nih.gov/pubmed/24729664 http://dx.doi.org/10.1155/2014/905463

Ejemplares similares

Silence of NLRP3 Suppresses Atherosclerosis and Stabilizes Plaques in Apolipoprotein E-Deficient Mice
por: Zheng, Fei, et al.
Publicado: (2014)

Atherosclerosis is exacerbated by chitinase-3-like-1 in amyloid precursor protein transgenic mice
por: Jung, Yu Yeon, et al.
Publicado: (2018)

Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis
por: Lee, Suh-Young, et al.
Publicado: (2022)

Chitinases and chitinase-like proteins as biomarkers in neurologic disorders
por: Pinteac, Rucsanda, et al.
Publicado: (2020)

Apolipoprotein E Genotype and the Relationship Between Chitinase 3–Like Protein 1 and Postoperative Delirium
por: Vasunilashorn, Sarinnapha, et al.
Publicado: (2020)

Human Chitinases and Chitinase-Like Proteins as Indicators for Inflammation and Cancer
por: Kzhyshkowska, Julia, et al.
Publicado: (2007)

Chitinase-3-like protein 1 levels in bipolar disorder
por: Sahin, Basak, et al.
Publicado: (2019)

Chitinase 3-like 1 is neurotoxic in primary cultured neurons
por: Matute-Blanch, Clara, et al.
Publicado: (2020)

Chitin, Chitinases and Chitinase-like Proteins in Allergic Inflammation and Tissue Remodeling
por: Lee, Chun Geun
Publicado: (2009)

The role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases
por: Mack, Ines, et al.
Publicado: (2015)

Neutrophils as a Source of Chitinases and Chitinase-Like Proteins in Type 2 Diabetes
por: Żurawska-Płaksej, Ewa, et al.
Publicado: (2015)

Chitinase-3 like-protein-1 function and its role in diseases
por: Zhao, Ting, et al.
Publicado: (2020)

RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis
por: Ma, Bing, et al.
Publicado: (2016)

Chitinase 3 like 1 suppresses the stability and activity of p53 to promote lung tumorigenesis
por: Park, Kyung-Ran, et al.
Publicado: (2020)

Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases – Current Concepts and Potential Applications
por: Przysucha, Natalia, et al.
Publicado: (2020)

Chitinase 3-like 1 promotes macrophage recruitment and angiogenesis in colorectal cancer
por: Kawada, Mayumi, et al.
Publicado: (2011)

Role of genetic variations of chitinase 3-like 1 in bronchial asthmatic patients
por: Abe, Kazuyuki, et al.
Publicado: (2018)

CSF chitinase 3-like-1 association with disability of primary progressive MS
por: Pérez-Miralles, Francisco, et al.
Publicado: (2020)

Differential expression of Chitinase 3‐Like 1 protein in appendicitis and appendix carcinomas
por: Zhang, Yong, et al.
Publicado: (2022)

Comparative Genomic Analysis of Chitinase and Chitinase-Like Genes in the African Malaria Mosquito (Anopheles gambiae)
por: Zhang, Jianzhen, et al.
Publicado: (2011)

Chitinase 3-Like 1 Protein Levels Are Elevated in Schistosoma haematobium Infected Children
por: Appleby, Laura J., et al.
Publicado: (2012)

Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms with Hepatocellular Carcinoma in Taiwan
por: Huang, Wayne Shih-Wei, et al.
Publicado: (2017)

Chitinase 3–like 1 and neurofilament light chain in CSF and CNS atrophy in MS
por: Schneider, Ruth, et al.
Publicado: (2020)

Diagnostic and prognostic value of serum Chitinase 3‐like protein 1 in hepatocellular carcinoma
por: Wang, Shuwei, et al.
Publicado: (2022)

Chitinase 3 like 1 contributes to the development of pulmonary vascular remodeling in pulmonary hypertension
por: Sun, Xiuna, et al.
Publicado: (2022)

Chitinase 3-like-1 Expression in the Microenvironment Is Associated with Neutrophil Infiltration in Bladder Cancer
por: Xiao, Ling-Yi, et al.
Publicado: (2023)

Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases
por: Mazur, Marzena, et al.
Publicado: (2021)

Gene Encoding Chitinase 3-Like 1 Protein (CHI3L1) is a Putative Oncogene
por: Kavsan, Vadym M., et al.
Publicado: (2011)

CHI3L1 (Chitinase 3 Like 1) upregulation is associated with macrophage signatures in esophageal cancer
por: Huang, Jing, et al.
Publicado: (2021)

Cells from the skin of patients with systemic sclerosis secrete chitinase 3-like protein 1
por: Ho, Yuen Yee, et al.
Publicado: (2014)

Chitinase-3-Like Protein 1 (YKL-40) Reflects the Severity of Symptoms in Atopic Dermatitis
por: Salomon, Joanna, et al.
Publicado: (2017)

Chitinase-3-Like Protein 1 (YKL-40) Is a New Biomarker of Inflammation in Psoriasis
por: Salomon, Joanna, et al.
Publicado: (2017)

Determination of chitinase 3-like 1 in cerebrospinal fluid in multiple sclerosis and other neurological diseases
por: Kušnierová, Pavlína, et al.
Publicado: (2020)

Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization
por: Kim, Eun Gyul, et al.
Publicado: (2020)

Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma
por: Wurm, Julian, et al.
Publicado: (2019)

Chitinase 3‐like 1 deficiency ameliorates liver fibrosis by promoting hepatic macrophage apoptosis
por: Higashiyama, Masaaki, et al.
Publicado: (2019)

Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19
por: Kamle, Suchitra, et al.
Publicado: (2021)

Role of Chitinase-3-like Protein 1 in Cardioprotection and Angiogenesis by Post-Infarction Exercise Training
por: Li, Zhuo, et al.
Publicado: (2022)

Chitinase-3 like-protein-1, matrix metalloproteinase -9 and positive intracranial arterial remodelling
por: Tang, Ming, et al.
Publicado: (2023)

Potential Roles and Future Perspectives of Chitinase 3-like 1 in Macrophage Polarization and the Development of Diseases
por: Zhao, Hailong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p6lt8j6q4h72lv1cmj6qochjjo