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The Application of Next Generation Sequencing in DNA Methylation Analysis

DNA methylation is a major form of epigenetic modification and plays essential roles in physiology and disease processes. In the human genome, about 80% of cytosines in the 56 million CpG sites are methylated to 5-methylcytosines. The methylation pattern of DNA is highly variable among cells types a...

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Detalles Bibliográficos
Autores principales: Zhang, Yingying, Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960863/
https://www.ncbi.nlm.nih.gov/pubmed/24710012
http://dx.doi.org/10.3390/genes1010085