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Correlation analysis between eGFR(cys) and SXscore in patients with diabetes
The aim of the present study was to explore the association between the cystatin C-based estimated glomerular filtration rate (eGFR(cys)) and the SYNTAX score (SXscore) in patients with diabetes. To the best of our knowledge, this correlation has not been reported previously. The eGFR(cys) and SXsco...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961135/ https://www.ncbi.nlm.nih.gov/pubmed/24669241 http://dx.doi.org/10.3892/etm.2014.1536 |
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author | YONG, ZHONG ZHU, LIYONG TAN, JUAN ZHU, SHAIHONG |
author_facet | YONG, ZHONG ZHU, LIYONG TAN, JUAN ZHU, SHAIHONG |
author_sort | YONG, ZHONG |
collection | PubMed |
description | The aim of the present study was to explore the association between the cystatin C-based estimated glomerular filtration rate (eGFR(cys)) and the SYNTAX score (SXscore) in patients with diabetes. To the best of our knowledge, this correlation has not been reported previously. The eGFR(cys) and SXscore from 612 consecutive patients with diabetes were retrospectively included in this study. The patients were angiographically diagnosed with coronary artery disease (CAD) between July 2010 and March 2012 at the Department of Endocrinology. The SXscore was calculated using a previously described SXscore algorithm. Pearson correlations were used to analyze the correlation between eGFR(cys) and SXscore. Patients with renal dysfunction were older, more often female and more likely to have a history of hypertension when compared with those with normal renal function. The eGFR(cys) values were significantly lower and the cystatin C levels were significantly higher in the highest SXscore group than those in other groups (P<0.001). Correlation analysis indicated that eGFR(cys) was negatively correlated with the SXscore (r=−0.7918, P<0.001). In addition, a significantly positive correlation was identified between levels of cystatin C and the SXscore (r=0.8891, P<0.001). In conclusion, eGFR(cys) is an independent predictor of SXscore in patients with diabetes. The eGFR(cys)-estimating method may be considered important in the assessment of the SXscore in patients with diabetes. |
format | Online Article Text |
id | pubmed-3961135 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-39611352014-03-25 Correlation analysis between eGFR(cys) and SXscore in patients with diabetes YONG, ZHONG ZHU, LIYONG TAN, JUAN ZHU, SHAIHONG Exp Ther Med Articles The aim of the present study was to explore the association between the cystatin C-based estimated glomerular filtration rate (eGFR(cys)) and the SYNTAX score (SXscore) in patients with diabetes. To the best of our knowledge, this correlation has not been reported previously. The eGFR(cys) and SXscore from 612 consecutive patients with diabetes were retrospectively included in this study. The patients were angiographically diagnosed with coronary artery disease (CAD) between July 2010 and March 2012 at the Department of Endocrinology. The SXscore was calculated using a previously described SXscore algorithm. Pearson correlations were used to analyze the correlation between eGFR(cys) and SXscore. Patients with renal dysfunction were older, more often female and more likely to have a history of hypertension when compared with those with normal renal function. The eGFR(cys) values were significantly lower and the cystatin C levels were significantly higher in the highest SXscore group than those in other groups (P<0.001). Correlation analysis indicated that eGFR(cys) was negatively correlated with the SXscore (r=−0.7918, P<0.001). In addition, a significantly positive correlation was identified between levels of cystatin C and the SXscore (r=0.8891, P<0.001). In conclusion, eGFR(cys) is an independent predictor of SXscore in patients with diabetes. The eGFR(cys)-estimating method may be considered important in the assessment of the SXscore in patients with diabetes. D.A. Spandidos 2014-04 2014-02-12 /pmc/articles/PMC3961135/ /pubmed/24669241 http://dx.doi.org/10.3892/etm.2014.1536 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles YONG, ZHONG ZHU, LIYONG TAN, JUAN ZHU, SHAIHONG Correlation analysis between eGFR(cys) and SXscore in patients with diabetes |
title | Correlation analysis between eGFR(cys) and SXscore in patients with diabetes |
title_full | Correlation analysis between eGFR(cys) and SXscore in patients with diabetes |
title_fullStr | Correlation analysis between eGFR(cys) and SXscore in patients with diabetes |
title_full_unstemmed | Correlation analysis between eGFR(cys) and SXscore in patients with diabetes |
title_short | Correlation analysis between eGFR(cys) and SXscore in patients with diabetes |
title_sort | correlation analysis between egfr(cys) and sxscore in patients with diabetes |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961135/ https://www.ncbi.nlm.nih.gov/pubmed/24669241 http://dx.doi.org/10.3892/etm.2014.1536 |
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