Cargando…
Development of a Novel, Single-Cycle Replicable Rift Valley Fever Vaccine
Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is an arbovirus that causes severe disease in humans and livestock in sub-Saharan African countries. Although the MP-12 strain of RVFV is a live attenuated vaccine candidate, neuroinvasiveness and neurovirulence of MP-12 in mice...
Autores principales: | Murakami, Shin, Terasaki, Kaori, Ramirez, Sydney I., Morrill, John C., Makino, Shinji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961198/ https://www.ncbi.nlm.nih.gov/pubmed/24651859 http://dx.doi.org/10.1371/journal.pntd.0002746 |
Ejemplares similares
-
Mechanistic Insight into the Host Transcription Inhibition Function of Rift Valley Fever Virus NSs and Its Importance in Virulence
por: Terasaki, Kaori, et al.
Publicado: (2016) -
A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice
por: Terasaki, Kaori, et al.
Publicado: (2018) -
Mechanistic insight into the efficient packaging of antigenomic S RNA into Rift Valley fever virus particles
por: Tercero, Breanna, et al.
Publicado: (2023) -
The Pathogenesis of Rift Valley Fever
por: Ikegami, Tetsuro, et al.
Publicado: (2011) -
Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA
por: Morrill, John C., et al.
Publicado: (2010)