Effect of tumor suppressor gene cyclin-dependent kinase inhibitor 2A wild-type and A148T mutant on the cell cycle of human ovarian cancer cells

Single-base substitution may affect the function of genes. This study identified a single-base substitution of G for A in codon 148 of cyclin-dependent kinase inhibitor 2A (CDKN2A/p16) by sequencing human ovarian cancer cell line UACC-1598. As a tumor suppressor gene, the expression of CDKN2A/p16 sh...

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Detalles Bibliográficos
Autores principales: BIAN, ZEHUA, YU, YANG, YANG, TERIGELE, QUAN, CHAO, SUN, WENJING, FU, SONGBIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961237/
https://www.ncbi.nlm.nih.gov/pubmed/24944698
http://dx.doi.org/10.3892/ol.2014.1867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961237/
https://www.ncbi.nlm.nih.gov/pubmed/24944698
http://dx.doi.org/10.3892/ol.2014.1867

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