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Effect of tumor suppressor gene cyclin-dependent kinase inhibitor 2A wild-type and A148T mutant on the cell cycle of human ovarian cancer cells

Single-base substitution may affect the function of genes. This study identified a single-base substitution of G for A in codon 148 of cyclin-dependent kinase inhibitor 2A (CDKN2A/p16) by sequencing human ovarian cancer cell line UACC-1598. As a tumor suppressor gene, the expression of CDKN2A/p16 sh...

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Detalles Bibliográficos
Autores principales:	BIAN, ZEHUA, YU, YANG, YANG, TERIGELE, QUAN, CHAO, SUN, WENJING, FU, SONGBIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961237/ https://www.ncbi.nlm.nih.gov/pubmed/24944698 http://dx.doi.org/10.3892/ol.2014.1867

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