Cargando…

Ectopic Fat Accumulation and Distant Organ-Specific Insulin Resistance in Japanese People with Nonalcoholic Fatty Liver Disease

OBJECTIVE: The aim of this study was to examine the association between ectopic fat and organ-specific insulin resistance (IR) in insulin-target organs in patients with nonalcoholic fatty liver disease (NAFLD). METHODS: Organ-specific IR in the liver (hepatic glucose production (HGP)×fasting plasma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kato, Ken-ichiro, Takamura, Toshinari, Takeshita, Yumie, Ryu, Yasuji, Misu, Hirofumi, Ota, Tsuguhito, Tokuyama, Kumpei, Nagasaka, Shoichiro, Matsuhisa, Munehide, Matsui, Osamu, Kaneko, Shuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961287/ https://www.ncbi.nlm.nih.gov/pubmed/24651470 http://dx.doi.org/10.1371/journal.pone.0092170

Ejemplares similares

Ursodeoxycholic acid potentiates dipeptidyl peptidase-4 inhibitor sitagliptin by enhancing glucagon-like peptide-1 secretion in patients with type 2 diabetes and chronic liver disease: a pilot randomized controlled and add-on study
por: Shima, Kosuke Robert, et al.
Publicado: (2018)

Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes
por: Misu, Hirofumi, et al.
Publicado: (2012)

Liver steatosis is associated with insulin resistance in skeletal muscle rather than in the liver in Japanese patients with non-alcoholic fatty liver disease
por: Kato, Ken-ichiro, et al.
Publicado: (2015)

Mealtime dosing of a rapid-acting insulin analog reduces glucose variability and suppresses daytime cardiac sympathetic activity: a randomized controlled study in hospitalized patients with type 2 diabetes
por: Kanamori, Takehiro, et al.
Publicado: (2018)

Effects of metformin and alogliptin on body composition in people with type 2 diabetes
por: Takeshita, Yumie, et al.
Publicado: (2018)

Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis
por: Kita, Yuki, et al.
Publicado: (2012)

Fat‐free mass and calf circumference as body composition indices to determine non‐exercise activity thermogenesis in patients with diabetes
por: Isobe, Yuki, et al.
Publicado: (2015)

Vildagliptin vs liraglutide as a second-line therapy switched from sitagliptin-based regimens in patients with type 2 diabetes: A randomized, parallel-group study
por: Takeshita, Yumie, et al.
Publicado: (2015)

Renoprotective effects of atorvastatin compared with pravastatin on progression of early diabetic nephropathy
por: Takazakura, Akiko, et al.
Publicado: (2015)

Bending of a vertical cannula without alarm during insulin pump therapy as a cause of unexpected hyperglycemia: A Japanese issue?
por: Kuroda, Kaori, et al.
Publicado: (2015)

Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver
por: Otoda, Toshiki, et al.
Publicado: (2013)

Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria
por: Nakamura, Seiji, et al.
Publicado: (2009)

Sitagliptin versus mitiglinide switched from mealtime dosing of a rapid-acting insulin analog in patients with type 2 diabetes: a randomized, parallel-group study
por: Takeshita, Yumie, et al.
Publicado: (2015)

p62‐mediated autophagy affects nutrition‐dependent insulin receptor substrate 1 dynamics in 3T3‐L1 preadipocytes
por: Igawa, Hirobumi, et al.
Publicado: (2018)

Histological Course of Nonalcoholic Fatty Liver Disease in Japanese Patients: Tight glycemic control, rather than weight reduction, ameliorates liver fibrosis
por: Hamaguchi, Erika, et al.
Publicado: (2010)

Concentration-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes
por: Iwakami, Satoshi, et al.
Publicado: (2011)

LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH
por: Takata, Noboru, et al.
Publicado: (2021)

Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population
por: Oo, Swe Mar, et al.
Publicado: (2018)

Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease
por: Kawaguchi, Kazunori, et al.
Publicado: (2021)

Study Protocol for Pleiotropic Effects and Safety of Sodium–Glucose Cotransporter 2 Inhibitor Versus Sulfonylurea in Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
por: Takeshita, Yumie, et al.
Publicado: (2020)

Nutrigenetic Interaction Between Apolipoprotein C3 Polymorphism and Fat Intake in People with Nonalcoholic Fatty Liver Disease
por: Yamamoto, Reina, et al.
Publicado: (2023)

Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E
por: Kobori, Masuko, et al.
Publicado: (2017)

Weight-adjusted lean body mass and calf circumference are protective against obesity-associated insulin resistance and metabolic abnormalities
por: Takamura, Toshinari, et al.
Publicado: (2017)

Corrigendum to ‘Weight-adjusted lean body mass and calf circumference are protective against obesity-associated insulin resistance and metabolic abnormalities’
por: Takamura, Toshinari, et al.
Publicado: (2017)

Effects of eicosapentaenoic acid on serum levels of selenoprotein P and organ‐specific insulin sensitivity in humans with dyslipidemia and type 2 diabetes
por: Takeshita, Yumie, et al.
Publicado: (2021)

Association between coefficients of variation of the R‐R intervals on electrocardiograms and post‐challenge hyperglycemia in patients with newly diagnosed type 2 diabetes
por: Nakade, Yusuke, et al.
Publicado: (2011)

Endogenous Selenoprotein P, a Liver-Derived Secretory Protein, Mediates Myocardial Ischemia/Reperfusion Injury in Mice
por: Chadani, Hiroshi, et al.
Publicado: (2018)

Comparison of Tofogliflozin and Glimepiride Effects on Nonalcoholic Fatty Liver Disease in Participants With Type 2 Diabetes: A Randomized, 48-Week, Open-Label, Active-Controlled Trial
por: Takeshita, Yumie, et al.
Publicado: (2022)

Reply to the Letter to the Editor by Li et al.: Bioinformatics Analysis in Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E
por: Kobori, Masuko, et al.
Publicado: (2017)

β-Cryptoxanthin Alleviates Diet-Induced Nonalcoholic Steatohepatitis by Suppressing Inflammatory Gene Expression in Mice
por: Kobori, Masuko, et al.
Publicado: (2014)

Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples
por: Sugiyama, Masakazu, et al.
Publicado: (2018)

Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease
por: Chen, Guanliang, et al.
Publicado: (2016)

Pleiotropic effects of sitagliptin versus voglibose in patients with type 2 diabetes inadequately controlled via diet and/or a single oral antihyperglycemic agent: a multicenter, randomized trial
por: Matsushima, Yukiko, et al.
Publicado: (2016)

Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments
por: Kitade, Hironori, et al.
Publicado: (2017)

CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status
por: Kitade, Hironori, et al.
Publicado: (2012)

Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up
por: Sakai, Yoshio, et al.
Publicado: (2021)

Metabolic and sympathovagal effects of bolus insulin glulisine versus basal insulin glargine therapy in people with type 2 diabetes: A randomized controlled study
por: Takeshita, Yumie, et al.
Publicado: (2020)

Roles of Chemokines and Chemokine Receptors in Obesity-Associated Insulin Resistance and Nonalcoholic Fatty Liver Disease
por: Xu, Liang, et al.
Publicado: (2015)

A novel PHEX mutation associated with vitamin D-resistant rickets
por: Sako, Saori, et al.
Publicado: (2019)

Ectopic Papillary Thyroid Cancer with Distant Metastasis
por: Vázquez, Oscar R., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bk6l2qhd034q28la6o56buemcm