A Forward Phenotypically Driven Unbiased Genetic Analysis of Host Genes That Moderate Herpes Simplex Virus Virulence and Stromal Keratitis in Mice

Both viral and host genetics affect the outcome of herpes simplex virus type 1 (HSV-1) infection in humans and experimental models. Little is known about specific host gene variants and molecular networks that influence herpetic disease progression, severity, and episodic reactivation. To identify s...

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Detalles Bibliográficos
Autores principales: Thompson, Richard L., Williams, Robert W., Kotb, Malak, Sawtell, Nancy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961320/
https://www.ncbi.nlm.nih.gov/pubmed/24651695
http://dx.doi.org/10.1371/journal.pone.0092342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961320/
https://www.ncbi.nlm.nih.gov/pubmed/24651695
http://dx.doi.org/10.1371/journal.pone.0092342

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