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A furin inhibitor downregulates osteosarcoma cell migration by downregulating the expression levels of MT1-MMP via the Wnt signaling pathway

This study aimed to explore the exact mechanism of the effect of a furin inhibitor on the migration and invasion of MG-63 and Saos-2 osteosarcoma cells. MG-63 and Saos-2 osteosarcoma cells were treated with regular culture medium in the presence or absence of 480 nM α1-antitrypsin Portland (α1-PDX)....

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Detalles Bibliográficos
Autores principales: LIU, BINGSHAN, LI, GUOJUN, WANG, XIAO, LIU, YANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961323/
https://www.ncbi.nlm.nih.gov/pubmed/24944664
http://dx.doi.org/10.3892/ol.2014.1839