The Ectodomain of TLR3 Receptor Is Required for Its Plasma Membrane Translocation

Toll-like receptor 3 (TLR3) is a dsRNA sensing receptor that is localized in the cellular compartments but also at the plasma membrane. Overexpression of UNC93B1 promoted localization of TLR3, but not other nucleic acid sensing TLRs, to the plasma membrane. Here we show that UNC93B1 itself is locali...

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Detalles Bibliográficos
Autores principales: Pohar, Jelka, Pirher, Nina, Benčina, Mojca, Manček-Keber, Mateja, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961339/
https://www.ncbi.nlm.nih.gov/pubmed/24651829
http://dx.doi.org/10.1371/journal.pone.0092391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961339/
https://www.ncbi.nlm.nih.gov/pubmed/24651829
http://dx.doi.org/10.1371/journal.pone.0092391

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