Cargando…

Fluorodeoxyglucose uptake in laryngeal carcinoma is associated with the expression of glucose transporter-1 and hypoxia-inducible-factor-1α and the phosphoinositide 3-kinase/protein kinase B pathway

High fluorodeoxyglucose (FDG) uptake by human carcinomas, including head and neck cancers, is associated with a poor prognosis. Glucose transporter-1 (Glut-1) is believed to be an intrinsic marker of hypoxia in malignant tumors. The expression of hypoxia-inducible factor-1α (HIF-1α) and correlated t...

Descripción completa

Detalles Bibliográficos
Autores principales:	ZHAO, KUI, YANG, SHU-YE, ZHOU, SHUI-HONG, DONG, MENG JIE, BAO, YANG-YANG, YAO, HONG-TIAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961369/ https://www.ncbi.nlm.nih.gov/pubmed/24944654 http://dx.doi.org/10.3892/ol.2014.1877

Ejemplares similares

Relationships between expression of glucose transporter protein-1 and hypoxia inducible factor-1α, prognosis and (18)F-FDG uptake in laryngeal and hypopharyngeal carcinomas
por: Shen, Li-Fang, et al.
Publicado: (2020)

Inhibition of phosphoinositide 3-kinase/Akt pathway decreases hypoxia inducible factor-1α expression and increases therapeutic efficacy of paclitaxel in human hypoxic gastric cancer cells
por: ZHANG, JING, et al.
Publicado: (2014)

Effect of Antisense Oligodeoxynucleotides Glucose Transporter-1 on Enhancement of Radiosensitivity of Laryngeal Carcinoma
por: Yan, Sen-Xiang, et al.
Publicado: (2013)

(18)F-Fluorodeoxyglucose Uptake and Tumor Hypoxia: Revisit (18)F-Fluorodeoxyglucose in Oncology Application
por: Li, Xiao-Feng, et al.
Publicado: (2014)

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
por: Huang, Xueqin, et al.
Publicado: (2023)

Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
por: Wood, C. David, et al.
Publicado: (2007)

Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases
por: Finlay, David K.
Publicado: (2012)

Molecular Dynamics Simulations to Investigate the Binding Mode of the Natural Product Liphagal with Phosphoinositide 3-Kinase α
por: Gao, Yanjuan, et al.
Publicado: (2016)

Notch-induced T cell development requires phosphoinositide-dependent kinase 1
por: Kelly, April P, et al.
Publicado: (2007)

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation
por: Levina, Aleksandra, et al.
Publicado: (2022)

3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib
por: Meraz, Ismail M., et al.
Publicado: (2023)

Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4
por: Nirula, Ajay, et al.
Publicado: (2006)

Sodium-Glucose Cotransporter-2 Inhibitors for Hyperglycemia in Phosphoinositide 3-kinase Pathway Inhibition
por: Weintraub, Michael A, et al.
Publicado: (2023)

Gene and protein expression of glucose transporter 1 and glucose transporter 3 in human laryngeal cancer—the relationship with regulatory hypoxia-inducible factor-1α expression, tumor invasiveness, and patient prognosis
por: Starska, Katarzyna, et al.
Publicado: (2014)

Phosphoinositide 3-Kinase Inhibitor-Induced Hyperglycemia
por: Shey, Susan, et al.
Publicado: (2021)

Apigenin inhibits the proliferation of adenoid cystic carcinoma via suppression of glucose transporter-1
por: FANG, JIN, et al.
Publicado: (2015)

Resveratrol inhibits hypoxia-induced proliferation and migration of pulmonary artery vascular smooth muscle cells by inhibiting the phosphoinositide 3-kinase/protein kinase B signaling pathway
por: Guan, Zhanjiang, et al.
Publicado: (2017)

Dihydrotestosterone induces SREBP-1 expression and lipogenesis through the phosphoinositide 3-kinase/Akt pathway in HaCaT cells
por: Zhou, Bing-rong, et al.
Publicado: (2012)

A novel phosphoinositide kinase Fab1 regulates biosynthesis of pathogenic aflatoxin in Aspergillus flavus
por: Yang, Mingkun, et al.
Publicado: (2020)

mRNA surveillance complex PELOTA–HBS1 regulates phosphoinositide-dependent protein kinase1 and plant growth
por: Kong, Wei, et al.
Publicado: (2021)

The 3-phosphoinositide–dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites
por: Hitz, Eva, et al.
Publicado: (2021)

The 3-Phosphoinositide-Dependent Protein Kinase 1 Inhibits Rod Photoreceptor Development
por: Xing, Tiaosi, et al.
Publicado: (2018)

Hepatocellular carcinoma serum derived exosomal HIF-1α induces phosphoinositide-3 kinase/protein kinase B signaling to induce the angiogenesis and proliferation of HCC
por: Xu, Qingyu, et al.
Publicado: (2019)

Phosphoinositide-3-Kinase Is the Primary Mediator of Phosphoinositide-Dependent Inhibition in Mammalian Olfactory Receptor Neurons
por: Ukhanov, Kirill, et al.
Publicado: (2016)

The Role of Phosphoinositide 3-Kinase Signaling in Intestinal Inflammation
por: Cahill, Catherine M., et al.
Publicado: (2012)

The role of phosphoinositide 3-kinase subunits in chronic thyroiditis
por: Wojciechowska-Durczynska, Katarzyna, et al.
Publicado: (2012)

Phosphoinositide 3-kinase: friend and foe in cardiovascular disease
por: Ghigo, Alessandra, et al.
Publicado: (2015)

The phosphoinositide 3-kinase pathway and therapy resistance in cancer
por: Brown, Kristin K., et al.
Publicado: (2015)

Phosphoinositides, kinases and adaptors coordinating endocytosis in Trypanosoma brucei
por: Manna, Paul T, et al.
Publicado: (2016)

Multiple Functions of Phosphoinositide-3 Kinase Enhancer (PIKE)
por: Chan, Chi Bun, et al.
Publicado: (2010)

Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment
por: Gyori, David, et al.
Publicado: (2017)

Psoriasiform eruptions secondary to phosphoinositide 3-kinase inhibition
por: Dewan, Anna K., et al.
Publicado: (2019)

Phosphoinositide 3′-Kinase γ Facilitates Polyomavirus Infection
por: Clark, Paul, et al.
Publicado: (2020)

Phosphoinositide 3-Kinases as Potential Targets for Thrombosis Prevention
por: Setiabakti, Natasha M., et al.
Publicado: (2022)

Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling
por: Lin, Richard Z., et al.
Publicado: (2019)

Full Activation of Kinase Protein Kinase B by Phosphoinositide-Dependent Protein Kinase-1 and Mammalian Target of Rapamycin Complex 2 Is Required for Early Natural Killer Cell Development and Survival
por: He, Junming, et al.
Publicado: (2021)

Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase
por: Liu, Jingxian, et al.
Publicado: (2019)

Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome
por: Lelièvre, Hélène, et al.
Publicado: (2008)

Expression and significance of glucose transporter-1, P-glycoprotein, multidrug resistance-associated protein and glutathione S-transferase-π in laryngeal carcinoma
por: MAO, ZHONG-PING, et al.
Publicado: (2015)

Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival
por: Thomas, Daniel, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8eo8t1htvkau54b4okfjpojr5a