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Activation of 2′ 5′-Oligoadenylate Synthetase by Stem Loops at the 5′-End of the West Nile Virus Genome
West Nile virus (WNV) has a positive sense RNA genome with conserved structural elements in the 5′ and 3′ -untranslated regions required for polyprotein production. Antiviral immunity to WNV is partially mediated through the production of a cluster of proteins known as the interferon stimulated gene...
Autores principales: | Deo, Soumya, Patel, Trushar R., Dzananovic, Edis, Booy, Evan P., Zeid, Khalid, McEleney, Kevin, Harding, Stephen E., McKenna, Sean A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961380/ https://www.ncbi.nlm.nih.gov/pubmed/24651762 http://dx.doi.org/10.1371/journal.pone.0092545 |
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