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Plasminogen Activator Inhibitor-1 Is Involved in Impaired Bone Repair Associated with Diabetes in Female Mice

Previous studies suggest that fracture healing is impaired in diabetes; however, the underlying mechanism remains unclear. Here, we investigated the roles of plasminogen activator inhibitor-1 (PAI-1) in the impaired bone repair process by using streptozotocin (STZ)-induced diabetic female wild-type...

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Detalles Bibliográficos
Autores principales: Mao, Li, Kawao, Naoyuki, Tamura, Yukinori, Okumoto, Katsumi, Okada, Kiyotaka, Yano, Masato, Matsuo, Osamu, Kaji, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961397/
https://www.ncbi.nlm.nih.gov/pubmed/24651693
http://dx.doi.org/10.1371/journal.pone.0092686