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ATM Alters the Otherwise Robust Chromatin Mobility at Sites of DNA Double-Strand Breaks (DSBs) in Human Cells

Ionizing radiation induces DNA double strand breaks (DSBs) which can lead to the formation of chromosome rearrangements through error prone repair. In mammalian cells the positional stability of chromatin contributes to the maintenance of genome integrity. DSBs exhibit only a small, submicron scale...

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Detalles Bibliográficos
Autores principales:	Becker, Annabelle, Durante, Marco, Taucher-Scholz, Gisela, Jakob, Burkhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961414/ https://www.ncbi.nlm.nih.gov/pubmed/24651490 http://dx.doi.org/10.1371/journal.pone.0092640

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