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Prostate Cancer Induced by Loss of Apc Is Restrained by TGFβ Signaling

Recent work with mouse models of prostate cancer (CaP) has shown that inactivation of TGFβ signaling in prostate epithelium can cooperate with deletion of the Pten tumor suppressor to drive locally aggressive cancer and metastatic disease. Here, we show that inactivating the TGFβ pathway by deleting...

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Detalles Bibliográficos
Autores principales:	Bjerke, Glen A., Pietrzak, Karolina, Melhuish, Tiffany A., Frierson Jr., Henry F., Paschal, Bryce M., Wotton, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961420/ https://www.ncbi.nlm.nih.gov/pubmed/24651496 http://dx.doi.org/10.1371/journal.pone.0092800

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