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Lymphadenoma of the salivary gland: Report of 10 cases

Lymphadenoma of the salivary gland is rare, and the typical characteristics of lymphadenoma remain poorly understood. The aim of this study was to analyze the experience of a single institution in the clinical diagnosis, treatment and prognosis of this type of tumor of the salivary gland. All cases...

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Autores principales: LIU, GUANGLONG, HE, JIE, ZHANG, CHUNYE, FU, SHUITING, HE, YUE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961462/
https://www.ncbi.nlm.nih.gov/pubmed/24944675
http://dx.doi.org/10.3892/ol.2014.1827
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author LIU, GUANGLONG
HE, JIE
ZHANG, CHUNYE
FU, SHUITING
HE, YUE
author_facet LIU, GUANGLONG
HE, JIE
ZHANG, CHUNYE
FU, SHUITING
HE, YUE
author_sort LIU, GUANGLONG
collection PubMed
description Lymphadenoma of the salivary gland is rare, and the typical characteristics of lymphadenoma remain poorly understood. The aim of this study was to analyze the experience of a single institution in the clinical diagnosis, treatment and prognosis of this type of tumor of the salivary gland. All cases of lymphadenoma diagnosed at the institution between 1996 and 2012 were analyzed. The clinical information (including age, gender and tumor location, process of tumor development, imaging data, surgical treatment and follow-up information) and pathological features were evaluated. All tumors occurred in the parotid glands; three cases were sebaceous lymphadenoma (two male and one female) and seven were non-sebaceous lymphadenoma (three male and four female). The average ages of the patients were 68.3 and 42.4 years for the sebaceous and non-sebaceous groups, respectively. The majority of cases (90%) were diagnosed as pleomorphic adenoma or adenolymphoma prior to surgery, but were confirmed as lymphadenoma by pathological analysis following surgery. During the follow-up period, which ranged between 3 and 36 months with a mean of 30 months, no recurrence of the lesion was identified and the quality of life was good for each patient. In conclusion, the diagnosis of salivary gland lymphadenoma should be based on the clinical and, in particular, the pathological manifestations of the disease. Immunohistochemistry is considered as a practical and helpful adjuvant method of the diagnosis for this type of tumor. Complete surgical resection is the first choice of treatment. Further exploration of the histological origin of lymphadenoma of the salivary gland is necessary due to the insufficient number of reported cases.
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spelling pubmed-39614622014-06-18 Lymphadenoma of the salivary gland: Report of 10 cases LIU, GUANGLONG HE, JIE ZHANG, CHUNYE FU, SHUITING HE, YUE Oncol Lett Articles Lymphadenoma of the salivary gland is rare, and the typical characteristics of lymphadenoma remain poorly understood. The aim of this study was to analyze the experience of a single institution in the clinical diagnosis, treatment and prognosis of this type of tumor of the salivary gland. All cases of lymphadenoma diagnosed at the institution between 1996 and 2012 were analyzed. The clinical information (including age, gender and tumor location, process of tumor development, imaging data, surgical treatment and follow-up information) and pathological features were evaluated. All tumors occurred in the parotid glands; three cases were sebaceous lymphadenoma (two male and one female) and seven were non-sebaceous lymphadenoma (three male and four female). The average ages of the patients were 68.3 and 42.4 years for the sebaceous and non-sebaceous groups, respectively. The majority of cases (90%) were diagnosed as pleomorphic adenoma or adenolymphoma prior to surgery, but were confirmed as lymphadenoma by pathological analysis following surgery. During the follow-up period, which ranged between 3 and 36 months with a mean of 30 months, no recurrence of the lesion was identified and the quality of life was good for each patient. In conclusion, the diagnosis of salivary gland lymphadenoma should be based on the clinical and, in particular, the pathological manifestations of the disease. Immunohistochemistry is considered as a practical and helpful adjuvant method of the diagnosis for this type of tumor. Complete surgical resection is the first choice of treatment. Further exploration of the histological origin of lymphadenoma of the salivary gland is necessary due to the insufficient number of reported cases. D.A. Spandidos 2014-04 2014-01-24 /pmc/articles/PMC3961462/ /pubmed/24944675 http://dx.doi.org/10.3892/ol.2014.1827 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
LIU, GUANGLONG
HE, JIE
ZHANG, CHUNYE
FU, SHUITING
HE, YUE
Lymphadenoma of the salivary gland: Report of 10 cases
title Lymphadenoma of the salivary gland: Report of 10 cases
title_full Lymphadenoma of the salivary gland: Report of 10 cases
title_fullStr Lymphadenoma of the salivary gland: Report of 10 cases
title_full_unstemmed Lymphadenoma of the salivary gland: Report of 10 cases
title_short Lymphadenoma of the salivary gland: Report of 10 cases
title_sort lymphadenoma of the salivary gland: report of 10 cases
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961462/
https://www.ncbi.nlm.nih.gov/pubmed/24944675
http://dx.doi.org/10.3892/ol.2014.1827
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