Reversal of CD8 T-Cell–Mediated Mucocutaneous Graft-Versus-Host-Like Disease by the JAK Inhibitor Tofacitinib

The utility of allogeneic hematopoietic stem cell transplantation is limited by graft-versus-host disease (GVHD), a significant cause of morbidity and mortality. Patients with GVHD exhibit cutaneous manifestations with histological features of interface dermatitis followed by scleroderma-like change...

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Detalles Bibliográficos
Autores principales: Okiyama, Naoko, Furumoto, Yasuko, Villarroel, Vadim A, Linton, Jay T, Tsai, Wanxia L, Gutermuth, Jan, Ghoreschi, Kamran, Gadina, Massimo, O'Shea, John J, Katz, Stephen I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961527/
https://www.ncbi.nlm.nih.gov/pubmed/24213371
http://dx.doi.org/10.1038/jid.2013.476

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