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Effect of Activated Charcoal on Apixaban Pharmacokinetics in Healthy Subjects
BACKGROUND: Activated charcoal is commonly used to manage overdose or accidental ingestion of medicines. This study evaluated the effect of activated charcoal on apixaban exposure in human subjects. METHODS: This was an open-label, three-treatment, three-period, randomized, crossover study of single...
Autores principales: | Wang, Xiaoli, Mondal, Sabiha, Wang, Jessie, Tirucherai, Giridhar, Zhang, Donglu, Boyd, Rebecca A., Frost, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961628/ https://www.ncbi.nlm.nih.gov/pubmed/24277644 http://dx.doi.org/10.1007/s40256-013-0055-y |
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