Cargando…

Structures of Complexes of a Metal-independent Glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-Acetylgalactosamine (UDP-GalNAc) and Its Hydrolysis Products

Mammalian members of glycosyltransferase family 6 (GT6) of the CAZy database have a GT-A fold containing a conserved Asp-X-Asp (DXD) sequence that binds an essential metal cofactor. Bacteroides ovatus GT6a represents a GT6 clade found in more than 30 Gram-negative bacteria that is similar in sequenc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pham, Tram T. K., Stinson, Brittany, Thiyagarajan, Nethaji, Lizotte-Waniewski, Michelle, Brew, Keith, Acharya, K. Ravi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961637/ https://www.ncbi.nlm.nih.gov/pubmed/24459149 http://dx.doi.org/10.1074/jbc.M113.545384

Ejemplares similares

Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity
por: Pedersen, Johannes W., et al.
Publicado: (2011)

The Synthesis of UDP-N-acetylglucosamine Is Essential for Bloodstream Form Trypanosoma brucei in Vitro and in Vivo and UDP-N-acetylglucosamine Starvation Reveals a Hierarchy in Parasite Protein Glycosylation
por: Stokes, Matthew J., et al.
Publicado: (2008)

Cytokines Alter IgA1 O-Glycosylation by Dysregulating C1GalT1 and ST6GalNAc-II Enzymes
por: Suzuki, Hitoshi, et al.
Publicado: (2014)

The conserved threonine-rich region of the HCF-1(PRO) repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities
por: Kapuria, Vaibhav, et al.
Publicado: (2018)

A Mucin-type O-Glycosyltransferase Modulates Cell Adhesion during Drosophila Development
por: Zhang, Liping, et al.
Publicado: (2008)

Unveiling the activation dynamics of a fold-switch bacterial glycosyltransferase by (19)F NMR
por: Liebau, Jobst, et al.
Publicado: (2020)

A Gene of the β3-Glycosyltransferase Family Encodes N-Acetylglucosaminyltransferase II Function in Trypanosoma brucei
por: Damerow, Manuela, et al.
Publicado: (2016)

Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes
por: Nonaka, Motohiro, et al.
Publicado: (2014)

UDP-Galactose 4′-Epimerase Activities toward UDP-Gal and UDP-GalNAc Play Different Roles in the Development of Drosophila melanogaster
por: Daenzer, Jennifer M. I., et al.
Publicado: (2012)

CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3(+) Dendritic Cells and a Subset of Monocytes
por: Huysamen, Cristal, et al.
Publicado: (2008)

TSG-6 Regulates Bone Remodeling through Inhibition of Osteoblastogenesis and Osteoclast Activation
por: Mahoney, David J., et al.
Publicado: (2008)

Identification of Neutrophil Granule Glycoproteins as Lewis(x)-containing Ligands Cleared by the Scavenger Receptor C-type Lectin
por: Graham, Sarah A., et al.
Publicado: (2011)

Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation
por: Barthel, Steven R., et al.
Publicado: (2011)

Early Murine T-lymphocyte Activation Is Accompanied by a Switch from N-Glycolyl- to N-Acetyl-neuraminic Acid and Generation of Ligands for Siglec-E
por: Redelinghuys, Pierre, et al.
Publicado: (2011)

Post-assembly Modification of Bordetella bronchiseptica O Polysaccharide by a Novel Periplasmic Enzyme Encoded by wbmE
por: King, Jerry D., et al.
Publicado: (2009)

Interleukin-6 Released from Fibroblasts Is Essential for Up-regulation of Matrix Metalloproteinase-1 Expression by U937 Macrophages in Coculture: CROSS-TALKING BETWEEN FIBROBLASTS AND U937 MACROPHAGES EXPOSED TO HIGH GLUCOSE
por: Sundararaj, Kamala P., et al.
Publicado: (2009)

Loss of α-Dystroglycan Laminin Binding in Epithelium-derived Cancers Is Caused by Silencing of LARGE
por: de Bernabé, Daniel Beltrán-Valero, et al.
Publicado: (2009)

A Human Embryonic Kidney 293T Cell Line Mutated at the Golgi α-Mannosidase II Locus
por: Crispin, Max, et al.
Publicado: (2009)

Rapid Purification and High Sensitivity Analysis of Heparan Sulfate from Cells and Tissues: TOWARD GLYCOMICS PROFILING
por: Guimond, Scott E., et al.
Publicado: (2009)

Trimeric Structure of Langerin
por: Feinberg, Hadar, et al.
Publicado: (2010)

Heparan Sulfate Chain Valency Controls Syndecan-4 Function in Cell Adhesion
por: Gopal, Sandeep, et al.
Publicado: (2010)

α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling
por: Kitazume, Shinobu, et al.
Publicado: (2010)

Glycomics Profiling of Chinese Hamster Ovary Cell Glycosylation Mutants Reveals N-Glycans of a Novel Size and Complexity
por: North, Simon J., et al.
Publicado: (2010)

Revised Role of Glycosaminoglycans in TAT Protein Transduction Domain-mediated Cellular Transduction
por: Gump, Jacob M., et al.
Publicado: (2010)

Prolectin, a Glycan-binding Receptor on Dividing B Cells in Germinal Centers
por: Graham, Sarah A., et al.
Publicado: (2009)

In Planta Protein Sialylation through Overexpression of the Respective Mammalian Pathway
por: Castilho, Alexandra, et al.
Publicado: (2010)

Role of the Netrin-like Domain of Procollagen C-Proteinase Enhancer-1 in the Control of Metalloproteinase Activity
por: Bekhouche, Mourad, et al.
Publicado: (2010)

Identification of Mono- and Disulfated N-Acetyl-lactosaminyl Oligosaccharide Structures as Epitopes Specifically Recognized by Humanized Monoclonal Antibody HMOCC-1 Raised against Ovarian Cancer
por: Shibata, Toshiaki K., et al.
Publicado: (2012)

Constitutive Expression of Inter-α-inhibitor (IαI) Family Proteins and Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) by Human Amniotic Membrane Epithelial and Stromal Cells Supporting Formation of the Heavy Chain-Hyaluronan (HC-HA) Complex
por: Zhang, Suzhen, et al.
Publicado: (2012)

Monocyte-to-Macrophage Differentiation: SYNTHESIS AND SECRETION OF A COMPLEX EXTRACELLULAR MATRIX
por: Chang, Mary Y., et al.
Publicado: (2012)

Transglutaminase-2 Interaction with Heparin: IDENTIFICATION OF A HEPARIN BINDING SITE THAT REGULATES CELL ADHESION TO FIBRONECTIN-TRANSGLUTAMINASE-2 MATRIX
por: Lortat-Jacob, Hugues, et al.
Publicado: (2012)

Chemical Structure of Trichomonas vaginalis Surface Lipoglycan: A ROLE FOR SHORT GALACTOSE (β1–4/3) N-ACETYLGLUCOSAMINE REPEATS IN HOST CELL INTERACTION
por: Ryan, Christopher M., et al.
Publicado: (2011)

Collagen VI, Conformation of A-domain Arrays and Microfibril Architecture
por: Beecher, Nicola, et al.
Publicado: (2011)

The Streptococcal Binding Site in the Gelatin-binding Domain of Fibronectin Is Consistent with a Non-linear Arrangement of Modules
por: Atkin, Kate E., et al.
Publicado: (2010)

β-N-Acetylhexosaminidases HEXO1 and HEXO3 Are Responsible for the Formation of Paucimannosidic N-Glycans in Arabidopsis thaliana
por: Liebminger, Eva, et al.
Publicado: (2011)

Redefinition of the Carbohydrate Binding Specificity of Helicobacter pylori BabA Adhesin
por: Benktander, John, et al.
Publicado: (2012)

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood
por: Jung, Stephanie M., et al.
Publicado: (2012)

Binding of N-Acetylglucosamine (GlcNAc) β1–6-branched Oligosaccharide Acceptors to β4-Galactosyltransferase I Reveals a New Ligand Binding Mode
por: Ramakrishnan, Boopathy, et al.
Publicado: (2012)

Significant Impact of Single N-Glycan Residues on the Biological Activity of Fc-based Antibody-like Fragments
por: Jez, Jakub, et al.
Publicado: (2012)

High Throughput Screening for Compounds That Alter Muscle Cell Glycosylation Identifies New Role for N-Glycans in Regulating Sarcolemmal Protein Abundance and Laminin Binding
por: Cabrera, Paula V., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_iefotecm5flu3u5vfq193d9ot6