Smoking and Pancreatic Disease

Smoking is a major risk factor for chronic pancreatitis and pancreatic cancer. However, the mechanisms through which it causes the diseases remain unknown. In the present manuscript we reviewed the latest knowledge gained on the effect of cigarette smoke and smoking compounds on cell signaling pathw...

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Detalles Bibliográficos
Autores principales: Edderkaoui, Mouad, Thrower, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961826/
https://www.ncbi.nlm.nih.gov/pubmed/24660091
http://dx.doi.org/10.4236/jct.2013.410A005
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author Edderkaoui, Mouad
Thrower, Edwin
author_facet Edderkaoui, Mouad
Thrower, Edwin
author_sort Edderkaoui, Mouad
collection PubMed
description Smoking is a major risk factor for chronic pancreatitis and pancreatic cancer. However, the mechanisms through which it causes the diseases remain unknown. In the present manuscript we reviewed the latest knowledge gained on the effect of cigarette smoke and smoking compounds on cell signaling pathways mediating both diseases. We also reviewed the effect of smoking on the pancreatic cell microenvironment including inflammatory cells and stellate cells.
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spelling pubmed-39618262014-03-21 Smoking and Pancreatic Disease Edderkaoui, Mouad Thrower, Edwin J Cancer Ther Article Smoking is a major risk factor for chronic pancreatitis and pancreatic cancer. However, the mechanisms through which it causes the diseases remain unknown. In the present manuscript we reviewed the latest knowledge gained on the effect of cigarette smoke and smoking compounds on cell signaling pathways mediating both diseases. We also reviewed the effect of smoking on the pancreatic cell microenvironment including inflammatory cells and stellate cells. 2013-11-01 /pmc/articles/PMC3961826/ /pubmed/24660091 http://dx.doi.org/10.4236/jct.2013.410A005 Text en Copyright © 2013 Mouad Edderkaoui, Edwin Thrower. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Edderkaoui, Mouad
Thrower, Edwin
Smoking and Pancreatic Disease
title Smoking and Pancreatic Disease
title_full Smoking and Pancreatic Disease
title_fullStr Smoking and Pancreatic Disease
title_full_unstemmed Smoking and Pancreatic Disease
title_short Smoking and Pancreatic Disease
title_sort smoking and pancreatic disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961826/
https://www.ncbi.nlm.nih.gov/pubmed/24660091
http://dx.doi.org/10.4236/jct.2013.410A005
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