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Progress and challenges in the computational prediction of gene function using networks: 2012-2013 update
In an opinion published in 2012, we reviewed and discussed our studies of how gene network-based guilt-by-association (GBA) is impacted by confounds related to gene multifunctionality. We found such confounds account for a significant part of the GBA signal, and as a result meaningfully evaluating a...
Autores principales: | Pavlidis, Paul, Gillis, Jesse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962002/ https://www.ncbi.nlm.nih.gov/pubmed/24715959 http://dx.doi.org/10.12688/f1000research.2-230.v1 |
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