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Progress and challenges in the computational prediction of gene function using networks: 2012-2013 update

In an opinion published in 2012, we reviewed and discussed our studies of how gene network-based guilt-by-association (GBA) is impacted by confounds related to gene multifunctionality. We found such confounds account for a significant part of the GBA signal, and as a result meaningfully evaluating a...

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Detalles Bibliográficos
Autores principales: Pavlidis, Paul, Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962002/
https://www.ncbi.nlm.nih.gov/pubmed/24715959
http://dx.doi.org/10.12688/f1000research.2-230.v1

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