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Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species-dependent activities of Lipid IVA in the mammalian LPS sensor system

A literature review concerning the unexpected species differences of the vertebrate innate immune response to lipid IVA was published in CSBJ prior to the present computational study to address the unpaired activity-sequence correlation of prototypic E. coli -type lipid A and its precursor lipid IVA...

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Detalles Bibliográficos
Autores principales:	Scior, Thomas, Lozano-Aponte, Jorge, Figueroa-Vazquez, Vianihuini, Yunes-Rojas, Julian A., Zähringer, Ulrich, Alexander, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962092/ https://www.ncbi.nlm.nih.gov/pubmed/24688739 http://dx.doi.org/10.5936/csbj.201305003

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