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Current progress in Structure-Based Rational Drug Design marks a new mindset in drug discovery
The past decade has witnessed a paradigm shift in preclinical drug discovery with structure-based drug design (SBDD) making a comeback while high-throughput screening (HTS) methods have continued to generate disappointing results. There is a deficit of information between identified hits and the man...
Autores principales: | Lounnas, Valère, Ritschel, Tina, Kelder, Jan, McGuire, Ross, Bywater, Robert P., Foloppe, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962124/ https://www.ncbi.nlm.nih.gov/pubmed/24688704 http://dx.doi.org/10.5936/csbj.201302011 |
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