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Dissecting complex polyketide biosynthesis
Numerous bioactive natural products are synthesised by modular polyketide synthases. These compounds can be made in high yield by native multienzyme assembly lines. However, formation of analogues by genetically engineered systems is often considerably less efficient. Biochemical studies on intact p...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962154/ https://www.ncbi.nlm.nih.gov/pubmed/24688670 http://dx.doi.org/10.5936/csbj.201210010 |