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ChromatoGate: A Tool for Detecting Base Mis-Calls in Multiple Sequence Alignments by Semi-Automatic Chromatogram Inspection

Automated DNA sequencers generate chromatograms that contain raw sequencing data. They also generate data that translates the chromatograms into molecular sequences of A, C, G, T, or N (undetermined) characters. Since chromatogram translation programs frequently introduce errors, a manual inspection...

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Detalles Bibliográficos
Autores principales: Alachiotis, Nikolaos, Vogiatzi, Emmanouella, Pavlidis, Pavlos, Stamatakis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962156/
https://www.ncbi.nlm.nih.gov/pubmed/24688709
http://dx.doi.org/10.5936/csbj.201303001