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Leveraging biological replicates to improve analysis in ChIP-seq experiments

ChIP-seq experiments identify genome-wide profiles of DNA-binding molecules including transcription factors, enzymes and epigenetic marks. Biological replicates are critical for reliable site discovery and are required for the deposition of data in the ENCODE and modENCODE projects. While early repo...

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Detalles Bibliográficos
Autores principales: Yang, Yajie, Fear, Justin, Hu, Jianhong, Haecker, Irina, Zhou, Lei, Renne, Rolf, Bloom, David, McIntyre, Lauren M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962196/
https://www.ncbi.nlm.nih.gov/pubmed/24688750
http://dx.doi.org/10.5936/csbj.201401002