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Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems

This mini-review discusses the current state of experimental and computational microbial consortia engineering with a focus on cellular factories. A discussion of promising ecological theories central to community resource usage is presented to facilitate interpretation of consortial designs. Recent...

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Detalles Bibliográficos
Autores principales: Bernstein, Hans C, Carlson, Ross P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962199/
https://www.ncbi.nlm.nih.gov/pubmed/24688677
http://dx.doi.org/10.5936/csbj.201210017
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author Bernstein, Hans C
Carlson, Ross P
author_facet Bernstein, Hans C
Carlson, Ross P
author_sort Bernstein, Hans C
collection PubMed
description This mini-review discusses the current state of experimental and computational microbial consortia engineering with a focus on cellular factories. A discussion of promising ecological theories central to community resource usage is presented to facilitate interpretation of consortial designs. Recent case studies exemplifying different resource usage motifs and consortial assembly templates are presented. The review also highlights in silico approaches to design and to analyze consortia with an emphasis on stoichiometric modeling methods. The discipline of microbial consortia engineering possesses a widely accepted potential to generate highly novel and effective bio-catalysts for applications from biofuels to specialty chemicals to enhanced mineral recovery.
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spelling pubmed-39621992014-03-31 Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems Bernstein, Hans C Carlson, Ross P Comput Struct Biotechnol J Mini Review This mini-review discusses the current state of experimental and computational microbial consortia engineering with a focus on cellular factories. A discussion of promising ecological theories central to community resource usage is presented to facilitate interpretation of consortial designs. Recent case studies exemplifying different resource usage motifs and consortial assembly templates are presented. The review also highlights in silico approaches to design and to analyze consortia with an emphasis on stoichiometric modeling methods. The discipline of microbial consortia engineering possesses a widely accepted potential to generate highly novel and effective bio-catalysts for applications from biofuels to specialty chemicals to enhanced mineral recovery. Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2012-12-01 /pmc/articles/PMC3962199/ /pubmed/24688677 http://dx.doi.org/10.5936/csbj.201210017 Text en © Bernstein and Carlson. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly cited.
spellingShingle Mini Review
Bernstein, Hans C
Carlson, Ross P
Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems
title Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems
title_full Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems
title_fullStr Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems
title_full_unstemmed Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems
title_short Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems
title_sort microbial consortia engineering for cellular factories: in vitro to in silico systems
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962199/
https://www.ncbi.nlm.nih.gov/pubmed/24688677
http://dx.doi.org/10.5936/csbj.201210017
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