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Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems
This mini-review discusses the current state of experimental and computational microbial consortia engineering with a focus on cellular factories. A discussion of promising ecological theories central to community resource usage is presented to facilitate interpretation of consortial designs. Recent...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962199/ https://www.ncbi.nlm.nih.gov/pubmed/24688677 http://dx.doi.org/10.5936/csbj.201210017 |
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author | Bernstein, Hans C Carlson, Ross P |
author_facet | Bernstein, Hans C Carlson, Ross P |
author_sort | Bernstein, Hans C |
collection | PubMed |
description | This mini-review discusses the current state of experimental and computational microbial consortia engineering with a focus on cellular factories. A discussion of promising ecological theories central to community resource usage is presented to facilitate interpretation of consortial designs. Recent case studies exemplifying different resource usage motifs and consortial assembly templates are presented. The review also highlights in silico approaches to design and to analyze consortia with an emphasis on stoichiometric modeling methods. The discipline of microbial consortia engineering possesses a widely accepted potential to generate highly novel and effective bio-catalysts for applications from biofuels to specialty chemicals to enhanced mineral recovery. |
format | Online Article Text |
id | pubmed-3962199 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Research Network of Computational and Structural Biotechnology (RNCSB) Organization |
record_format | MEDLINE/PubMed |
spelling | pubmed-39621992014-03-31 Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems Bernstein, Hans C Carlson, Ross P Comput Struct Biotechnol J Mini Review This mini-review discusses the current state of experimental and computational microbial consortia engineering with a focus on cellular factories. A discussion of promising ecological theories central to community resource usage is presented to facilitate interpretation of consortial designs. Recent case studies exemplifying different resource usage motifs and consortial assembly templates are presented. The review also highlights in silico approaches to design and to analyze consortia with an emphasis on stoichiometric modeling methods. The discipline of microbial consortia engineering possesses a widely accepted potential to generate highly novel and effective bio-catalysts for applications from biofuels to specialty chemicals to enhanced mineral recovery. Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2012-12-01 /pmc/articles/PMC3962199/ /pubmed/24688677 http://dx.doi.org/10.5936/csbj.201210017 Text en © Bernstein and Carlson. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly cited. |
spellingShingle | Mini Review Bernstein, Hans C Carlson, Ross P Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems |
title | Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems |
title_full | Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems |
title_fullStr | Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems |
title_full_unstemmed | Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems |
title_short | Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems |
title_sort | microbial consortia engineering for cellular factories: in vitro to in silico systems |
topic | Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962199/ https://www.ncbi.nlm.nih.gov/pubmed/24688677 http://dx.doi.org/10.5936/csbj.201210017 |
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