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Exploring Compound Promiscuity Patterns and Multi-Target Activity Spaces
Compound promiscuity is rationalized as the specific interaction of a small molecule with multiple biological targets (as opposed to non-specific binding events) and represents the molecular basis of polypharmacology, an emerging theme in drug discovery and chemical biology. This concise review focu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962225/ https://www.ncbi.nlm.nih.gov/pubmed/24688751 http://dx.doi.org/10.5936/csbj.201401003 |