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Regulation of Pituitary MT1 Melatonin Receptor Expression by Gonadotrophin-Releasing Hormone (GnRH) and Early Growth Response Factor-1 (Egr-1): In Vivo and In Vitro Studies
Melatonin receptor expression exhibits profound developmental changes through poorly understood mechanisms. In mammals, a current model suggests that pubertal reactivation of gonadotrophin-releasing hormone (GnRH) secretion down-regulates MT1 melatonin receptors in pituitary gonadotroph cells, via t...
Autores principales: | Bae, Sung-Eun, Wright, Ian K., Wyse, Cathy, Samson-Desvignes, Nathalie, Le Blanc, Pascale, Laroche, Serge, Hazlerigg, David G., Johnston, Jonathan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962332/ https://www.ncbi.nlm.nih.gov/pubmed/24658054 http://dx.doi.org/10.1371/journal.pone.0090056 |
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