Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo

Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediate...

Descripción completa

Detalles Bibliográficos
Autores principales: Sandin, Linda C, Eriksson, Fredrik, Ellmark, Peter, Loskog, Angelica SI, Tötterman, Thomas H, Mangsbo, Sara M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962508/
https://www.ncbi.nlm.nih.gov/pubmed/24701377
http://dx.doi.org/10.4161/onci.27614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962508/
https://www.ncbi.nlm.nih.gov/pubmed/24701377
http://dx.doi.org/10.4161/onci.27614

Ejemplares similares