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Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo
Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962508/ https://www.ncbi.nlm.nih.gov/pubmed/24701377 http://dx.doi.org/10.4161/onci.27614 |