BREAKING THE “HARMONY” OF TNF-α SIGNALING FOR CANCER TREATMENT

Tumor necrosis factor-alpha (TNF-α) binds to two distinct receptors, TNFR1/p55 and TNFR2/p75. TNF-α is implicated in the processes of tumor growth, survival, differentiation, invasion, metastases, secretion of cytokines and pro-angiogenic factors. We have shown that TNFR2/p75 signaling promotes isch...

Descripción completa

Detalles Bibliográficos
Autores principales: Sasi, Sharath P., Yan, Xinhua, Enderling, Heiko, Park, Daniel, Gilbert, Hui-Ya, Curry, Cindy, Coleman, Christina, Hlatky, Lynn, Qin, Gangjian, Kishore, Raj, Goukassian, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962797/
https://www.ncbi.nlm.nih.gov/pubmed/22158049
http://dx.doi.org/10.1038/onc.2011.567

Ejemplares similares

Ejemplares similares