Molecular Basis of a Dominant T Cell Response to an HIV Reverse Transcriptase 8-mer Epitope Presented by the Protective Allele HLA-B*51:01

CD8(+) CTL responses directed toward the HLA-B*51:01–restricted HIV-RT(128–135) epitope TAFTIPSI (TI8) are associated with long-term nonprogression to AIDS. Clonotypic analysis of responses to B51-TI8 revealed a public clonotype using TRAV17/TRBV7-3 TCR genes in six out of seven HLA-B*51:01(+) patie...

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Detalles Bibliográficos
Autores principales: Motozono, Chihiro, Kuse, Nozomi, Sun, Xiaoming, Rizkallah, Pierre J., Fuller, Anna, Oka, Shinichi, Cole, David K., Sewell, Andrew K., Takiguchi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2014
Materias:
Molecular and Structural Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962895/
https://www.ncbi.nlm.nih.gov/pubmed/24600035
http://dx.doi.org/10.4049/jimmunol.1302667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962895/
https://www.ncbi.nlm.nih.gov/pubmed/24600035
http://dx.doi.org/10.4049/jimmunol.1302667

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