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Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis

INTRODUCTION: An increasing number of clinical and epidemiological studies suggest a possible association between attention-deficit/hyperactivity disorder (ADHD) and obesity/overweight. However, overall evidence is mixed. Given the public health relevance of ADHD and obesity/overweight, understandin...

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Autores principales: Cortese, Samuele, Moreira Maia, Carlos Renato, Rohde, Luis Augusto, Morcillo-Peñalver, Carmen, Faraone, Stephen V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963068/
https://www.ncbi.nlm.nih.gov/pubmed/24643169
http://dx.doi.org/10.1136/bmjopen-2013-004541
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author Cortese, Samuele
Moreira Maia, Carlos Renato
Rohde, Luis Augusto
Morcillo-Peñalver, Carmen
Faraone, Stephen V
author_facet Cortese, Samuele
Moreira Maia, Carlos Renato
Rohde, Luis Augusto
Morcillo-Peñalver, Carmen
Faraone, Stephen V
author_sort Cortese, Samuele
collection PubMed
description INTRODUCTION: An increasing number of clinical and epidemiological studies suggest a possible association between attention-deficit/hyperactivity disorder (ADHD) and obesity/overweight. However, overall evidence is mixed. Given the public health relevance of ADHD and obesity/overweight, understanding whether and to what extent they are associated is paramount to plan intervention and prevention strategies. We describe the protocol of a systematic review and meta-analysis aimed at assessing the prevalence of obesity/overweight in individuals with ADHD versus those without ADHD. METHODS AND ANALYSIS: We will include studies of any design (except case reports or case series) comparing the prevalence of obesity and/or overweight in children or adults with and without ADHD (or hyperkinetic disorder). We will search an extensive number of databases including PubMed, Ovid databases, Web of Knowledge and Thomson-Reuters databases, ERIC and CINAHL. No restrictions of language will be applied. We will also contact experts in the field for possible unpublished or in press data. Primary and additional outcomes will be the prevalence of obesity and overweight, respectively. We will combine ORs using random-effects models in STATA V.12.0. The quality of the study will be assessed primarily using the Newcastle-Ottawa Scale. Subgroup meta-analyses will be conducted according to participants’ age (children vs adults) and study setting (clinical vs general population). We will explore the feasibility of conducting meta-regression analyses to assess the moderating effect of age, gender, socioeconomic status, study setting, geographic location of the study (low-income, middle-income countries vs high-income countries), definition of obesity, method to assess ADHD, psychiatric comorbidities and medication status. ETHICS AND DISSEMINATION: No ethical issues are foreseen. The results will be published in a peer-reviewed journal and presented at national and international conferences of psychiatry, psychology, obesity and paediatrics. REGISTRATION: PROSPERO-National Institute of Health Research (NIHR) Prospective Register of Systematic Reviews (CRD42013006410).
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spelling pubmed-39630682014-03-24 Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis Cortese, Samuele Moreira Maia, Carlos Renato Rohde, Luis Augusto Morcillo-Peñalver, Carmen Faraone, Stephen V BMJ Open Mental Health INTRODUCTION: An increasing number of clinical and epidemiological studies suggest a possible association between attention-deficit/hyperactivity disorder (ADHD) and obesity/overweight. However, overall evidence is mixed. Given the public health relevance of ADHD and obesity/overweight, understanding whether and to what extent they are associated is paramount to plan intervention and prevention strategies. We describe the protocol of a systematic review and meta-analysis aimed at assessing the prevalence of obesity/overweight in individuals with ADHD versus those without ADHD. METHODS AND ANALYSIS: We will include studies of any design (except case reports or case series) comparing the prevalence of obesity and/or overweight in children or adults with and without ADHD (or hyperkinetic disorder). We will search an extensive number of databases including PubMed, Ovid databases, Web of Knowledge and Thomson-Reuters databases, ERIC and CINAHL. No restrictions of language will be applied. We will also contact experts in the field for possible unpublished or in press data. Primary and additional outcomes will be the prevalence of obesity and overweight, respectively. We will combine ORs using random-effects models in STATA V.12.0. The quality of the study will be assessed primarily using the Newcastle-Ottawa Scale. Subgroup meta-analyses will be conducted according to participants’ age (children vs adults) and study setting (clinical vs general population). We will explore the feasibility of conducting meta-regression analyses to assess the moderating effect of age, gender, socioeconomic status, study setting, geographic location of the study (low-income, middle-income countries vs high-income countries), definition of obesity, method to assess ADHD, psychiatric comorbidities and medication status. ETHICS AND DISSEMINATION: No ethical issues are foreseen. The results will be published in a peer-reviewed journal and presented at national and international conferences of psychiatry, psychology, obesity and paediatrics. REGISTRATION: PROSPERO-National Institute of Health Research (NIHR) Prospective Register of Systematic Reviews (CRD42013006410). BMJ Publishing Group 2014-03-18 /pmc/articles/PMC3963068/ /pubmed/24643169 http://dx.doi.org/10.1136/bmjopen-2013-004541 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Mental Health
Cortese, Samuele
Moreira Maia, Carlos Renato
Rohde, Luis Augusto
Morcillo-Peñalver, Carmen
Faraone, Stephen V
Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis
title Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis
title_full Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis
title_fullStr Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis
title_full_unstemmed Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis
title_short Prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis
title_sort prevalence of obesity in attention-deficit/hyperactivity disorder: study protocol for a systematic review and meta-analysis
topic Mental Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963068/
https://www.ncbi.nlm.nih.gov/pubmed/24643169
http://dx.doi.org/10.1136/bmjopen-2013-004541
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