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Potential Mechanisms of Aberrant DNA Hypomethylation on the X Chromosome in Uterine Leiomyomas

We recently found that aberrant DNA hypomethylation is more common on the X chromosome than on other chromosomes in uterine leiomyomas by genome-wide DNA methylation profiling. To investigate the mechanism of aberrant hypomethylation on the X chromosome in uterine leiomyomas, we analyzed methylome a...

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Detalles Bibliográficos
Autores principales: SATO, Shun, MAEKAWA, Ryo, YAMAGATA, Yoshiaki, ASADA, Hiromi, TAMURA, Isao, LEE, Lifa, OKADA, Maki, TAMURA, Hiroshi, SUGINO, Norihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963299/
https://www.ncbi.nlm.nih.gov/pubmed/24291816
http://dx.doi.org/10.1262/jrd.2013-095

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