Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

Peripheral T-cell lymphomas (PTCLs) are a heterogeneous and poorly understood group of non Hodgkin lymphomas(1,2). Here we combined whole exome sequencing of 12 tumor-normal DNA pairs, RNAseq analysis and targeted deep sequencing to identify new genetic alterations in PTCL transformation. These anal...

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Detalles Bibliográficos
Autores principales: Palomero, Teresa, Couronné, Lucile, Khiabanian, Hossein, Kim, Mi-Yeon, Ambesi-Impiombato, Alberto, Perez-Garcia, Arianne, Carpenter, Zachary, Abate, Francesco, Allegretta, Maddalena, Haydu, J. Erika, Jiang, Xiaoyu, Lossos, Izidore S., Nicolas, Concha, Balbin, Milagros, Bastard, Christian, Bhagat, Govind, Piris, Miguel Angel, Campo, Elias, Bernard, Olivier, Rabadan, Raul, Ferrando, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963408/
https://www.ncbi.nlm.nih.gov/pubmed/24413734
http://dx.doi.org/10.1038/ng.2873

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