Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya

Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in early 2012. This follows a period of six conse...

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Autores principales: Agoti, Charles N., Gitahi, Caroline W., Medley, Graham F., Cane, Patricia A., Nokes, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Part 2 Epidemiology and Impact of Respiratory Virus Infections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963446/
https://www.ncbi.nlm.nih.gov/pubmed/23782406
http://dx.doi.org/10.1111/irv.12131
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author Agoti, Charles N.
Gitahi, Caroline W.
Medley, Graham F.
Cane, Patricia A.
Nokes, D. James
author_facet Agoti, Charles N.
Gitahi, Caroline W.
Medley, Graham F.
Cane, Patricia A.
Nokes, D. James
author_sort Agoti, Charles N.
collection PubMed
description Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in early 2012. This follows a period of six consecutive respiratory syncytial virus (RSV) epidemics with 100% BA dominance among group B isolates. The new strains appear only distantly related to BA variants and to previously circulating SAB1 viruses last seen in the district in 2005, suggesting that they were circulating elsewhere undetected. These results are of relevance to an understanding of RSV persistence.
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spelling pubmed-39634462014-03-25 Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya Agoti, Charles N. Gitahi, Caroline W. Medley, Graham F. Cane, Patricia A. Nokes, D. James Influenza Other Respir Viruses Part 2 Epidemiology and Impact of Respiratory Virus Infections Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in early 2012. This follows a period of six consecutive respiratory syncytial virus (RSV) epidemics with 100% BA dominance among group B isolates. The new strains appear only distantly related to BA variants and to previously circulating SAB1 viruses last seen in the district in 2005, suggesting that they were circulating elsewhere undetected. These results are of relevance to an understanding of RSV persistence. John Wiley and Sons Inc. 2013-06-20 2013-11 /pmc/articles/PMC3963446/ /pubmed/23782406 http://dx.doi.org/10.1111/irv.12131 Text en © 2013 John Wiley & Sons Ltd. Influenza and Other Respiratory Viruses published by John Wiley & Sons This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Part 2 Epidemiology and Impact of Respiratory Virus Infections
Agoti, Charles N.
Gitahi, Caroline W.
Medley, Graham F.
Cane, Patricia A.
Nokes, D. James
Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya
title Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya
title_full Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya
title_fullStr Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya
title_full_unstemmed Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya
title_short Identification of group B respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya
title_sort identification of group b respiratory syncytial viruses that lack the 60‐nucleotide duplication after six consecutive epidemics of total ba dominance at coastal kenya
topic Part 2 Epidemiology and Impact of Respiratory Virus Infections
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963446/
https://www.ncbi.nlm.nih.gov/pubmed/23782406
http://dx.doi.org/10.1111/irv.12131
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