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The effect of cyclosporin-A on peri-operative myocardial injury in adult patients undergoing coronary artery bypass graft surgery: a randomised controlled clinical trial
OBJECTIVE: Cyclosporin-A (CsA) has been reported to reduce myocardial infarct size in both the experimental and clinical settings. This protective effect is dependent on its ability to prevent the opening of the mitochondrial permeability transition pore, a critical determinant of cell death in the...
Autores principales: | Hausenloy, DJ, Kunst, G, Boston-Griffiths, E, Kolvekar, S, Chaubey, S, John, L, Desai, J, Yellon, DM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963550/ https://www.ncbi.nlm.nih.gov/pubmed/24488610 http://dx.doi.org/10.1136/heartjnl-2013-304845 |
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