Cargando…

Comparative Expression Study of the Endo–G Protein Coupled Receptor (GPCR) Repertoire in Human Glioblastoma Cancer Stem-like Cells, U87-MG Cells and Non Malignant Cells of Neural Origin Unveils New Potential Therapeutic Targets

Glioblastomas (GBMs) are highly aggressive, invasive brain tumors with bad prognosis and unmet medical need. These tumors are heterogeneous being constituted by a variety of cells in different states of differentiation. Among these, cells endowed with stem properties, tumor initiating/propagating pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fève, Marie, Saliou, Jean-Michel, Zeniou, Maria, Lennon, Sarah, Carapito, Christine, Dong, Jihu, Van Dorsselaer, Alain, Junier, Marie-Pierre, Chneiweiss, Hervé, Cianférani, Sarah, Haiech, Jacques, Kilhoffer, Marie-Claude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963860/ https://www.ncbi.nlm.nih.gov/pubmed/24662753 http://dx.doi.org/10.1371/journal.pone.0091519

Ejemplares similares

Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy
por: Chen, Wanyin, et al.
Publicado: (2016)

Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells
por: Zeniou, Maria, et al.
Publicado: (2015)

WNK1 kinase and its partners Akt, SGK1 and NBC-family Na(+)/HCO3(−) cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling
por: Chen, Wanyin, et al.
Publicado: (2018)

Quiescence status of glioblastoma stem-like cells involves remodelling of Ca(2+) signalling and mitochondrial shape
por: Aulestia, Francisco J., et al.
Publicado: (2018)

The anti‐hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ‐dependent inhibition of the AKT pathway
por: Assad Kahn, Suzana, et al.
Publicado: (2016)

Personalized medicine and education: the challenge
por: Haiech, Jacques, et al.
Publicado: (2012)

Extended investigation of tube-gel sample preparation: a versatile and simple choice for high throughput quantitative proteomics
por: Muller, Leslie, et al.
Publicado: (2018)

Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter
por: Zimmermann, Michael, et al.
Publicado: (2010)

Ca(2+)-Dependent Transcriptional Repressors KCNIP and Regulation of Prognosis Genes in Glioblastoma
por: Néant, Isabelle, et al.
Publicado: (2018)

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
por: Krishnan, Arunkumar, et al.
Publicado: (2014)

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state
por: Frottin, Frédéric, et al.
Publicado: (2016)

Multi-omics dataset to decipher the complexity of drug resistance in diffuse large B-cell lymphoma
por: Fornecker, Luc-Matthieu, et al.
Publicado: (2019)

Multi-OMICS analyses unveil STAT1 as a potential modifier gene in mevalonate kinase deficiency
por: Carapito, Raphael, et al.
Publicado: (2018)

ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition
por: Bakhos-Douaihy, Dalal, et al.
Publicado: (2019)

Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells
por: Saurty-Seerunghen, Mirca S., et al.
Publicado: (2019)

Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth
por: Fareh, Mohamed, et al.
Publicado: (2017)

CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors
por: Patru, Cristina, et al.
Publicado: (2010)

Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation
por: Lesueur, Paul, et al.
Publicado: (2018)

Data in support of metabolic reprogramming in transformed mouse cortical astrocytes: A proteomic study
por: Bentaib, Azeddine, et al.
Publicado: (2014)

A Proteomic View of Cellular Responses to Anticancer Quinoline-Copper Complexes
por: Dalzon, Bastien, et al.
Publicado: (2019)

LOXL3 Silencing Affected Cell Adhesion and Invasion in U87MG Glioma Cells
por: Laurentino, Talita de S., et al.
Publicado: (2021)

Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness
por: Bogeas, Alexandra, et al.
Publicado: (2017)

Overview of methodologies for T-cell receptor repertoire analysis
por: Rosati, Elisa, et al.
Publicado: (2017)

Holothurians have a reduced GPCR and odorant receptor-like repertoire compared to other echinoderms
por: Marquet, Nathalie, et al.
Publicado: (2020)

Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture
por: Dague, Etienne, et al.
Publicado: (2022)

Broadening the repertoire of melanoma-associated T-cell epitopes
por: Frøsig, Thomas Mørch, et al.
Publicado: (2015)

GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation
por: Drube, J., et al.
Publicado: (2022)

Activation mode of the eukaryotic m(2)G(10) tRNA methyltransferase Trm11 by its partner protein Trm112
por: Bourgeois, Gabrielle, et al.
Publicado: (2017)

TRAIL and Paclitaxel Synergize to Kill U87 Cells and U87-Derived Stem-Like Cells in Vitro
por: Qiu, Bo, et al.
Publicado: (2012)

G Protein-Coupled Receptor 87 (GPR87) Promotes Cell Proliferation in Human Bladder Cancer Cells
por: Zhang, Xia, et al.
Publicado: (2015)

CELF2 Sustains a Proliferating/OLIG2+ Glioblastoma Cell Phenotype via the Epigenetic Repression of SOX3
por: Turchi, Laurent, et al.
Publicado: (2023)

The Shape of the Lymphocyte Receptor Repertoire: Lessons from the B Cell Receptor
por: Jackson, Katherine J. L., et al.
Publicado: (2013)

Topology and expressed repertoire of the Felis catus T cell receptor loci
por: Radtanakatikanon, Araya, et al.
Publicado: (2020)

Special Issue “GPCR: Roles in Cell Development and Disease”
por: Lattanzi, Roberta, et al.
Publicado: (2023)

Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo
por: Kerbrat, Stéphane, et al.
Publicado: (2015)

Structure-guided development of heterodimer-selective GPCR ligands
por: Hübner, Harald, et al.
Publicado: (2016)

Mitochondria Transcription Factor A: A Putative Target for the Effect of Melatonin on U87MG Malignant Glioma Cell Line
por: Franco, Daiane G., et al.
Publicado: (2018)

Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia
por: Schleiss, Cedric, et al.
Publicado: (2021)

Quantitative assessment of T-cell repertoire recovery after hematopoietic stem cell transplantation
por: van Heijst, Jeroen W J, et al.
Publicado: (2013)

The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation
por: Gauthier, Laurent R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_avnkcgegf8bvtdfi8vt0gl0ns9