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Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study
OBJECTIVE: We investigated factors associated with masked and white-coat hypertension in a Swiss population-based sample. METHODS: The Swiss Kidney Project on Genes in Hypertension is a family-based cross-sectional study. Office and 24-hour ambulatory blood pressure were measured using validated dev...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963885/ https://www.ncbi.nlm.nih.gov/pubmed/24663506 http://dx.doi.org/10.1371/journal.pone.0092522 |
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author | Alwan, Heba Pruijm, Menno Ponte, Belen Ackermann, Daniel Guessous, Idris Ehret, Georg Staessen, Jan A. Asayama, Kei Vuistiner, Philippe Younes, Sandrine Estoppey Paccaud, Fred Wuerzner, Grégoire Pechere-Bertschi, Antoinette Mohaupt, Markus Vogt, Bruno Martin, Pierre-Yves Burnier, Michel Bochud, Murielle |
author_facet | Alwan, Heba Pruijm, Menno Ponte, Belen Ackermann, Daniel Guessous, Idris Ehret, Georg Staessen, Jan A. Asayama, Kei Vuistiner, Philippe Younes, Sandrine Estoppey Paccaud, Fred Wuerzner, Grégoire Pechere-Bertschi, Antoinette Mohaupt, Markus Vogt, Bruno Martin, Pierre-Yves Burnier, Michel Bochud, Murielle |
author_sort | Alwan, Heba |
collection | PubMed |
description | OBJECTIVE: We investigated factors associated with masked and white-coat hypertension in a Swiss population-based sample. METHODS: The Swiss Kidney Project on Genes in Hypertension is a family-based cross-sectional study. Office and 24-hour ambulatory blood pressure were measured using validated devices. Masked hypertension was defined as office blood pressure<140/90 mmHg and daytime ambulatory blood pressure≥135/85 mmHg. White-coat hypertension was defined as office blood pressure≥140/90 mmHg and daytime ambulatory blood pressure<135/85 mmHg. Mixed-effect logistic regression was used to examine the relationship of masked and white-coat hypertension with associated factors, while taking familial correlations into account. High-normal office blood pressure was defined as systolic/diastolic blood pressure within the 130–139/85–89 mmHg range. RESULTS: Among the 652 participants included in this analysis, 51% were female. Mean age (±SD) was 48 (±18) years. The proportion of participants with masked and white coat hypertension was respectively 15.8% and 2.6%. Masked hypertension was associated with age (odds ratio (OR) = 1.02, p = 0.012), high-normal office blood pressure (OR = 6.68, p<0.001), and obesity (OR = 3.63, p = 0.001). White-coat hypertension was significantly associated with age (OR = 1.07, p<0.001) but not with education, family history of hypertension, or physical activity. CONCLUSIONS: Our findings suggest that physicians should consider ambulatory blood pressure monitoring for older individuals with high-normal office blood pressure and/or who are obese. |
format | Online Article Text |
id | pubmed-3963885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-39638852014-03-27 Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study Alwan, Heba Pruijm, Menno Ponte, Belen Ackermann, Daniel Guessous, Idris Ehret, Georg Staessen, Jan A. Asayama, Kei Vuistiner, Philippe Younes, Sandrine Estoppey Paccaud, Fred Wuerzner, Grégoire Pechere-Bertschi, Antoinette Mohaupt, Markus Vogt, Bruno Martin, Pierre-Yves Burnier, Michel Bochud, Murielle PLoS One Research Article OBJECTIVE: We investigated factors associated with masked and white-coat hypertension in a Swiss population-based sample. METHODS: The Swiss Kidney Project on Genes in Hypertension is a family-based cross-sectional study. Office and 24-hour ambulatory blood pressure were measured using validated devices. Masked hypertension was defined as office blood pressure<140/90 mmHg and daytime ambulatory blood pressure≥135/85 mmHg. White-coat hypertension was defined as office blood pressure≥140/90 mmHg and daytime ambulatory blood pressure<135/85 mmHg. Mixed-effect logistic regression was used to examine the relationship of masked and white-coat hypertension with associated factors, while taking familial correlations into account. High-normal office blood pressure was defined as systolic/diastolic blood pressure within the 130–139/85–89 mmHg range. RESULTS: Among the 652 participants included in this analysis, 51% were female. Mean age (±SD) was 48 (±18) years. The proportion of participants with masked and white coat hypertension was respectively 15.8% and 2.6%. Masked hypertension was associated with age (odds ratio (OR) = 1.02, p = 0.012), high-normal office blood pressure (OR = 6.68, p<0.001), and obesity (OR = 3.63, p = 0.001). White-coat hypertension was significantly associated with age (OR = 1.07, p<0.001) but not with education, family history of hypertension, or physical activity. CONCLUSIONS: Our findings suggest that physicians should consider ambulatory blood pressure monitoring for older individuals with high-normal office blood pressure and/or who are obese. Public Library of Science 2014-03-24 /pmc/articles/PMC3963885/ /pubmed/24663506 http://dx.doi.org/10.1371/journal.pone.0092522 Text en © 2014 Alwan et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Alwan, Heba Pruijm, Menno Ponte, Belen Ackermann, Daniel Guessous, Idris Ehret, Georg Staessen, Jan A. Asayama, Kei Vuistiner, Philippe Younes, Sandrine Estoppey Paccaud, Fred Wuerzner, Grégoire Pechere-Bertschi, Antoinette Mohaupt, Markus Vogt, Bruno Martin, Pierre-Yves Burnier, Michel Bochud, Murielle Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study |
title | Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study |
title_full | Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study |
title_fullStr | Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study |
title_full_unstemmed | Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study |
title_short | Epidemiology of Masked and White-Coat Hypertension: The Family-Based SKIPOGH Study |
title_sort | epidemiology of masked and white-coat hypertension: the family-based skipogh study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963885/ https://www.ncbi.nlm.nih.gov/pubmed/24663506 http://dx.doi.org/10.1371/journal.pone.0092522 |
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