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Three Weeks of Murine Hindlimb Unloading Induces Shifts from B to T and from Th to Tc Splenic Lymphocytes in Absence of Stress and Differentially Reduces Cell-Specific Mitogenic Responses

Extended space missions are known to induce stress and immune dysregulation. Hindlimb unloading is a ground-based model used to reproduce most spaceflight conditions. The aim of this study was to better characterize the consequences of prolonged exposure to hindlimb unloading on murine splenic lymph...

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Detalles Bibliográficos
Autores principales: Gaignier, Fanny, Schenten, Véronique, De Carvalho Bittencourt, Marcelo, Gauquelin-Koch, Guillemette, Frippiat, Jean-Pol, Legrand-Frossi, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963916/
https://www.ncbi.nlm.nih.gov/pubmed/24664102
http://dx.doi.org/10.1371/journal.pone.0092664

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