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Three Weeks of Murine Hindlimb Unloading Induces Shifts from B to T and from Th to Tc Splenic Lymphocytes in Absence of Stress and Differentially Reduces Cell-Specific Mitogenic Responses
Extended space missions are known to induce stress and immune dysregulation. Hindlimb unloading is a ground-based model used to reproduce most spaceflight conditions. The aim of this study was to better characterize the consequences of prolonged exposure to hindlimb unloading on murine splenic lymph...
Autores principales: | Gaignier, Fanny, Schenten, Véronique, De Carvalho Bittencourt, Marcelo, Gauquelin-Koch, Guillemette, Frippiat, Jean-Pol, Legrand-Frossi, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963916/ https://www.ncbi.nlm.nih.gov/pubmed/24664102 http://dx.doi.org/10.1371/journal.pone.0092664 |
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