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Adaptive Gene Regulation in the Striatum of RGS9-Deficient Mice

BACKGROUND: RGS9-deficient mice show drug-induced dyskinesia but normal locomotor activity under unchallenged conditions. RESULTS: Genes related to Ca(2+) signaling and their functions were regulated in RGS9-deficient mice. CONCLUSION: Changes in Ca(2+) signaling that compensate for RGS9 loss-of-fun...

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Detalles Bibliográficos
Autores principales: Busse, Kathy, Strotmann, Rainer, Strecker, Karl, Wegner, Florian, Devanathan, Vasudharani, Gohla, Antje, Schöneberg, Torsten, Schwarz, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963927/
https://www.ncbi.nlm.nih.gov/pubmed/24663062
http://dx.doi.org/10.1371/journal.pone.0092605